Purine và Pyrimidines


Định nghĩa

Purines và Pyrimidines là những bazơ nitơ làm nên 2 loại bazo nucleotide khác nhau đó là DNA và RNA. Các bazo nito carbon 2 vòng AdenineGuaninePurine, trong khi đó các base một vòng Nito-Carbon như ThymineCytosinePyrimidines

Purines(L) and Pyrimidine(R) molecules, where Black= Carbon, White=Hydrogen, Blue=Nitrogen

Các phân tử Purines(trái) và Pyrimidine(phải) , Black= Carbon, White=Hydrogen, Blue=Nitrogen

So sánh
  Purines Pyrimidine
Function: Production of RNA and DNA, proteins and starches, the regulation of enzymes and cell signaling. Production of RNA and DNA, proteins and starches, the regulation of enzymes and cell signaling.
Nucleobases: Adenine and guanine Cytosine, thymine, uracil
Structure: A pyrimidine ring fused to a imidazole ring. Contains two carbon-nitrogen rings and four nitrogen atoms. Contains one carbon-nitrogen ring and two nitrogen atoms.
Melting point: 214 °C, 487 K, 417 °F 20–22 °C
Type of Compound: Heterocyclic aromatic organic compound Heterocyclic aromatic organic compound
Molecular formula: C5H4N4 C4H4N2
Molar mass: 120.11 g mol−1 80.088 g mol-1
MeSH: Purine Pyrimidine
SMILES: c1c2c(nc[nH]2)ncn1 C1=CN=CN=C1
Introduction (from Wikipedia): A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. It is isomeric with two other forms of diazine.
CAS number: 120-73-0 289-95-2 Y
PubChem: 1044 9260
Synthesis in Lab: Traube Purine Synthesis Biginelli Reaction
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